[Blood lactate as prognostic marker in critically ill children: a problem related to production or clearance?].

نویسنده

  • Ricardo Ronco
چکیده

Suggested citation: Ronco R. Blood lactate as prognostic marker in critically ill children: a problem related to production or clearance? J Pediatr (Rio J). 2005;81:271-2. The temporal evolution of blood lactate levels has been widely used as a prognostic marker in critically ill patients, especially in the unstable phase. In the study published by Koliski et al.1 in this issue of Jornal de Pediatria, blood lactate levels were serially measured in critically ill children admitted to the ICU during the first 48 hours. The children were divided into group A, with lactate levels > to 18 mg/dl (2 mmol/l) (n = 50), and into group B, with lactate < 18 mg/dl (n = 25).

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Lactate revisited : is lactate monitoring beneficial for ICU patients ? REVIEw

Blood lactate levels are frequently measured in critically ill patients. Whilst these measurements are known to be accurate, for the correct interpretation of hyperlactataemia, it is essential to have sufficient understanding of anaerobic and aerobic mechanisms of production and clearance. The consistency of the prognostic value emphasizes the place of lactate measurement in the risk-stratifica...

متن کامل

[Blood lactate concentration as prognostic marker in critically ill children].

OBJECTIVE To assess the use of lactate as a marker of tissue hypoperfusion and as a prognostic index in critically ill patients. METHODS Prospective, longitudinal, observational study of 75 patients admitted to the pediatric ICU of Hospital de Clínicas of Universidade Federal do Paraná, between November 1998 and May 1999. According to the lactate level on admission, patients were divided into...

متن کامل

Lactate clearance as a useful biomarker for the prediction of all-cause mortality in critically ill patients: a systematic review study protocol

INTRODUCTION Arterial lactate is a reflection of balance between lactate production and clearance. Accumulating lactate may be a marker of global hypoxia or hypoperfusion. Lactate clearance is the reduction of lactate concentrations with interventional strategies, and it has been associated with increased risk of death in critically ill patients. However, conflicting results exist, which mandat...

متن کامل

Pharmacokinetic Behavior of Theophylline following PEEP in Critically Ill Patients with Acute Lung Injury

The effect of Positive End Expiratory Pressure (PEEP) on the hepatic elimination of low to moderate extraction ratio drugs has not been clearly defined. We prospectively investigated the effect of PEEP on the clearance of theophylline in 30 (20 males and 10 females) intubated critically ill adult patients with acute lung injury/acute respiratory distress syndrome (ALI/ARDS). The Mean (±SD) age ...

متن کامل

Pharmacokinetic Behavior of Theophylline following PEEP in Critically Ill Patients with Acute Lung Injury

The effect of Positive End Expiratory Pressure (PEEP) on the hepatic elimination of low to moderate extraction ratio drugs has not been clearly defined. We prospectively investigated the effect of PEEP on the clearance of theophylline in 30 (20 males and 10 females) intubated critically ill adult patients with acute lung injury/acute respiratory distress syndrome (ALI/ARDS). The Mean (±SD) age ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Jornal de pediatria

دوره 81 4  شماره 

صفحات  -

تاریخ انتشار 2005